After the epidemic, how to change the disease control reform?

After every major epidemic, there will always be a lot of reflection, which is the reason for the continuous progress of mankind, also known as learning from a pit. After SARS in 2003, China’s disease prevention and control system was given an opportunity to upgrade: a nationwide unified network direct reporting system for infectious diseases was established, and a case of "unexplained" pneumonia was specially designed in order to avoid the failure of reporting some diseases that have not been clearly defined for the time being; Established the Emergency Regulations for Public Health Emergencies, which stipulated a four-level emergency response mechanism; In many places, the health and epidemic prevention stations were renamed as centers for disease prevention and control, which clarified the establishment standards and improved the administrative level of the units … However, at the end of last year, the sudden COVID-19 epidemic gave us a real test of the achievements of the disease control system construction in the past 17 years, and the results were not satisfactory, exposing many problems.   

What are the main problems?   

(1) The direct reporting system of epidemic situation, which has been built with huge investment, is not running smoothly. 

(B) In the cry of strengthening the construction of disease control system, the number of disease control professionals has decreased compared with 2003. According to the Statistical Bulletin on the Development of Health Care in China in 2019, there are 188,000 people in the Center for Disease Control and Prevention, including 140,000 health technicians, which are 20,000 and 19,000 fewer than in 2003 respectively. 

(C) CDC system, people floating, brain drain accelerated. In June, 2019, at a seminar held in the State Council Development Research Center, Ceng Guang, chief epidemiologist of China Center for Disease Control and Prevention, said: Due to various problems accumulated for a long time and the further decline in income due to recent policy reasons, people in the disease control system are floating and the brain drain is accelerating. In the past three years, there have been as many as 100 young and middle-aged backbones lost from the National Center for Disease Control and Prevention alone, and the brain drain from disease control institutions in some places may be more serious. 

(4) The number of disease control institutions has decreased, and some places have even merged disease control institutions in the name of reform. In 2003, there were 3,584 national centers for disease control and prevention (epidemic prevention stations), and by the end of 2019, there were only 3,403 centers, a decrease of 181. In July 2018, Liaoning Province issued the red-headed document "Optimization and Integration Plan of Provincial Public Welfare Institutions", which reorganized and integrated the provincial and municipal disease control and health supervision departments. After the integration, only provincial disease control remained, and disease control and health supervision institutions below the provincial level were integrated and will no longer exist. 

(5) The county-level CDC is beset with "diseases" and its business development is stagnant and retrogressive. Professional and technical personnel are in short supply, and there is a serious shortage of staff; Aging infrastructure and insufficient investment; The channel of working funds is single; Lack of incentive and restraint performance appraisal system, lack of enthusiasm for disease control cadres.    

Reform is imperative! How to change it?   

Gao Fu suggested.   

According to the report of China Youth Daily on May 27th, Gao Fu, director of China Center for Disease Control and Prevention, who attended the third session of the 13th Chinese People’s Political Consultative Conference, called for speeding up the reform of the disease control system. He proposed to strengthen the core competence of disease control institutions and improve their "professional voice".   

He said that the new pneumonia epidemic has exposed the shortcomings of China’s major epidemic prevention and control system and public health system construction. As the main force of epidemic prevention and control, CDC has not fully played its role in early warning and monitoring, epidemiological investigation, and the proposal and implementation of prevention and control measures, and is faced with problems such as insufficient capacity, professional voice can not meet the requirements of modern disease prevention and control management and the increasingly diverse needs of the masses. The existing problems include: the CDC’s "unequal power and responsibility", the responsibility to put forward prevention and control strategies, the lack of decision-making power and discourse power to deal with the epidemic, and the "disconnection between administrative decision-making and technical strategies", and the CDC experts can only exercise the right of suggestion and cannot participate in decision-making; There is only a relationship of guidance and guidance between the superior and the subordinate disease control institutions, which makes it difficult to form an effective joint force in dealing with the epidemic situation. The division of labor and cooperation mechanism between disease prevention and control institutions and medical institutions is not perfect.

The administrative functions of disease prevention and control are decentralized. The disease prevention, control and emergency functions of the national health administrative department are scattered in many departments, such as disease prevention and control bureau, medical management and emergency office. There is a lot of interference in the details of prevention and control, and there is no comprehensive coordination. According to Gao Fu, from 2010 to 2018, the total number of CDC staff at all levels in China decreased by 3.9%, among which the number of professional technicians mainly practicing doctors decreased by 10.8%.

In terms of funds, the share of medical and health expenditure of CDC decreased from 2.9% to 2.4%. He stressed that the key to the reform of the disease prevention and control system "is not whether it has administrative power, but that the technical work is not subject to administrative intervention and maintains its independent technology and authority." To this end, he suggested clarifying the responsibilities of the administrative department and the technical department.

According to the law, CDC has the right to formulate and publish prevention and control strategies and technical plans, and is responsible for monitoring, investigating, handling, early warning and evaluating the epidemic situation. He suggested, "Give the CDC decision-making power in the field of professional affairs and reduce the micro-management and direct management of the CDC by the health administrative department. Explore the establishment of a mechanism for reporting public health work and major issues directly to the leaders in charge of the government, and directly release epidemic information with the authorization of the government. " In addition, he suggested strengthening the awareness and ability of coordination, strengthening the management of higher-level disease control institutions to lower-level disease control institutions, implementing vertical business management of major public health service projects under the jurisdiction of the central government, and strengthening the national disease control system. On the afternoon of June 2nd, General Secretary of the Supreme Leader presided over a symposium of experts and scholars and delivered an important speech. He emphasized that the disease prevention and control system is an important guarantee for protecting people’s health, ensuring public health safety and maintaining economic and social stability. We should base ourselves on more accurate and effective prevention, and intensify reform in rationalizing the system and mechanism, clarifying the functional orientation, and improving professional ability.

It is necessary to establish a stable investment mechanism for public health undertakings, improve the basic conditions for disease prevention and control, and improve public health services.

It is necessary to optimize and improve the function setting of disease prevention and control institutions and establish a division of labor and cooperation mechanism linked up and down.

It is necessary to strengthen the capacity building of national disease prevention and control institutions and strengthen their technology, ability and talent reserve. It is necessary to improve the linkage mechanism between disease control institutions and urban and rural communities, strengthen the disease prevention responsibilities of township hospitals and community health service centers, and consolidate the grassroots foundation of joint prevention and control.

It is necessary to innovate the coordination mechanism of medical care and prevention, and establish a mechanism of mutual restriction between personnel communication, information communication, resources communication and supervision and supervision.

It is necessary to strengthen the construction of disease control talent team, establish a talent training and use mechanism that adapts to the modern disease control system, and stabilize the grassroots disease control team.

It is necessary to build a number of high-level public health colleges and focus on cultivating talents who can solve practical problems such as pathogen identification, epidemic situation research and transmission law research, on-site epidemiological investigation and laboratory testing.

It is imperative to strengthen the ability of early monitoring and early warning, improve the monitoring system of infectious diseases and public health emergencies, improve the monitoring mechanism of unexplained diseases and abnormal health events, improve the sensitivity and accuracy of evaluation and monitoring, establish a multi-point trigger mechanism of intelligent early warning, improve the multi-channel monitoring and early warning mechanism, and improve the ability of real-time analysis and centralized judgment.

It is necessary to strengthen the construction of laboratory testing network and improve the ability of infectious disease detection. It is necessary to establish a collaborative monitoring mechanism between public health institutions and medical institutions, give play to the role of grass-roots sentinel, and achieve early detection, early reporting and early disposal.

It is necessary to improve the response plan system for public health emergencies, set up health emergency teams by classification, and cover the fields of situation judgment, epidemiological investigation, medical treatment, laboratory testing, community guidance, and material deployment. It is necessary to strengthen the knowledge reserve and training exercises of grassroots health personnel and enhance the ability of pre-disposal. It is necessary to carry out in-depth publicity and education on health emergency knowledge, and improve the people’s awareness of public health emergencies and their ability to prevent self-help and mutual aid.

Party committees and governments at all levels should establish regular research and deployment of health and health work mechanisms such as prevention and control of major epidemics, so as to ensure clear instructions, orderly systems, smooth implementation.

Hubei exploration   

On June 10th, the Seventh Plenary Session of the 11th CPC Hubei Provincial Committee was held in Wuhan. The meeting discussed the Opinions of Hubei Provincial People’s Government on Promoting the Reform of Disease Prevention and Control System and Public Health System, and decided to take the lead in domestic exploration, plan the reform of medical and health system as a whole, systematically reshape the public health system, and improve the system and mechanism of major epidemic prevention and control. Ying Yong, secretary of Hubei Provincial Party Committee, attended the meeting and delivered a speech. He pointed out that the prevention and control of the epidemic situation reflected the problems of imperfect network, unclear functions and separation of medical care and prevention in our province.

It is necessary to reform the disease control system in accordance with the unified arrangements of the CPC Central Committee. Straighten out the system and mechanism, clarify the functional orientation, and enhance the professional ability. Strengthen the administrative functions of disease control institutions, implement the responsibility of supervision and supervision, and the main person in charge of disease control institutions is also a member of the health department at the same level. 

Explore and promote the "first-class security and second-class management", implement the "two permits" in detail, allow disease control institutions to break through the current wage control level of public institutions, allow medical and health technical services to be provided on the basis of completing approved tasks, and further stimulate the endogenous motivation of disease control institutions. Strengthen the construction of disease control talents. Disease control institutions should strengthen monitoring and early warning functions, and effectively strengthen the construction of hardware facilities and infectious disease detection capabilities. The coordination of medical care and prevention should be the top priority.

Try out the system of "chief public health officer" in the health department. Formulate a list of public health responsibilities, improve public health service projects, and innovate the coordination mechanism between disease control institutions and medical institutions around the establishment of a mechanism of mutual restraint between personnel communication, information communication, resources communication and supervision and supervision. It is imperative to enhance early monitoring and early warning capabilities. The premise of epidemic monitoring and early warning is that the sources of epidemic information are unblocked and data are shared openly. It is necessary to improve the monitoring system of infectious diseases and public health emergencies, and establish a multi-point trigger mechanism of intelligent early warning to achieve early detection, early reporting and early disposal. 

Lao Xu suggested.   

(a) the implementation of epidemic reporting according to law, reduce human intervention, give full play to the state invested heavily in the establishment of the network is said to be relatively advanced epidemic reporting system. (two) strengthen the training of disease prevention and control professionals. First of all, we should plan the disease prevention and control system and the construction of talent team from the strategic height of national long-term stability. Huang Qifan once suggested that the training of public health and epidemic prevention talents must be expanded in scale and improved in quality, and double-class universities should be encouraged to set up high-quality public health colleges, rather than only medical colleges to set up this major; Build a national key university of public health and epidemic prevention, such as "China University of Public Health", pay equal attention to teaching and scientific research, cultivate high-end public health and epidemic prevention talents for the country, and concentrate on establishing a research system and laboratory system of public health and epidemic prevention, gather high-end scientific and technological talents from all over the world, and undertake cutting-edge research work in the field of public health in China and even the world. 

(3) In deepening the reform of the medical and health system, we should make overall plans for the reform of the disease control system. In particular, it should be noted that the disease control system can only be strengthened, not weakened; The talent team can only be steadily strengthened, and it cannot be floating and brain drain; The reform of disease control can only take a more professional road, establish the authority of disease control because of its specialty, and increase the right to speak in decision-making, instead of taking an administrative road. Disease prevention and control should be incorporated into the national security strategy, and an elite team that is professional, authoritative and trusted by all parties should be established, rather than an administrative grease. 

(four) pay close attention to the capacity building of grassroots disease control institutions. Create the first line of defense for disease prevention and control.  

Chengdu announces the sixth batch of municipal intangible cultural heritage projects.

On April 15th, the list of the sixth batch of representative municipal intangible cultural heritage projects in Chengdu was officially announced. This time, a total of 39 projects were selected as municipal intangible cultural heritage, among which there were many traditional folk activities loved by citizens, such as Chengdu Temple Fair of Wuhou Temple, You Xi Shen Fang, Dragon Boat Festival, Spring Festival in West Sichuan, and traditional skills such as cooked oil and sea pepper, which gathered the collective memory of old Chengdu people.

The sixth batch of Chengdu-level intangible cultural heritage announced this time is divided into seven categories, including traditional music, traditional dance and traditional skills. In 39 projects, Qiang flute performance and production skills, as well as Wuhou Temple Chengdu Temple Fair, Youxi Shenfang and other folk customs were selected. However, the most noteworthy thing in this list is that 17 items are all traditional techniques, including traditional production techniques such as Pujiang bean curd, Tianhui bean curd, Xindu Osmanthus Jelly, Chengdu Third Artillery and even Chengdu hot pot. In the future, these protected cooking techniques will ensure that they will always be "familiar recipes and familiar tastes". (Reporter   Wu Xiaoling)

High fever to 40℃! Influenza has entered a high incidence period, how to prevent it scientifically →

near future

Influenza, mainly influenza A, has entered a high incidence period.

Two weeks in a row

Pediatrics in major hospitals in our city have seen a peak of medical treatment.

The topic of influenza has attracted much attention.

So, how should children be prevented and treated scientifically?

it is reported

Recently, the number of influenza patients in outpatient and emergency departments has increased greatly.

Most of them are infected with influenza A virus.

And the patients are mainly children.

According to doctors, influenza A is an acute respiratory infectious disease. Once children are infected, they are prone to high fever with a body temperature of 39℃ to 40℃. The incubation period of influenza A is very short, usually only 1 to 3 days.

Doctors reminded that vaccination with influenza vaccine can significantly reduce the risk of serious complications. The most important thing to prevent influenza is to maintain good personal hygiene habits, including wearing masks, washing hands frequently, and often ventilating, and trying to avoid going to crowded places during the flu season. Once you have symptoms such as high fever, chills, fatigue, muscle pain, loss of appetite, you must seek medical attention in time.

The National CDC also reminded

There is a risk of COVID-19 epidemic rebounding in winter and spring, and the national influenza epidemic is still at a high level. It is predicted that during the Spring Festival, most parts of the country will still face the risk of alternating or co-epidemic of influenza, syncytial virus, mycoplasma infection and other respiratory infectious diseases. Everyone should do a good job in health protection and respond scientifically.

Is the flu the same as the common cold?

What are the disinfection methods for influenza virus?

Let’s take a look

Original title: "High fever to 40 C! Influenza has entered a high incidence period, how to prevent it scientifically → "

Read the original text

Experts talk about the difference between Covid-19 and SARS: it not only attacks the lungs, but also implicates the heart and kidneys.

  On the evening of February 19th, Tong Zhaohui, vice president of Beijing Chaoyang Hospital, Jiang Rongmeng, chief physician of the Second Department of Infectious Diseases of beijing ditan hospital, and Wu Anhua, director of the Department of Sensory Control of Xiangya Hospital of Central South University, and other three experts from the Central Steering Group held a press conference on the severe treatment in COVID-19, introducing the characteristics and treatment of severe and critical patients in COVID-19.

  It has been more than a month since Tong Zhaohui arrived in Wuhan on January 18th. At the press conference, he introduced that through this period of clinical observation, it was found that the age groups of severe and critically ill patients in COVID-19 were mainly over 50 years old and 60 years old, and they often had more basic diseases, such as hypertension, diabetes, coronary heart disease, and some had kidney and cerebrovascular diseases.

  What is the difference compared with SARS?

  "You may know that SARS patients in 2003 were young and middle-aged. In fact, this time they were all older and had basic diseases." Tong Zhaohui said that compared with SARS, the age and foundation of patients are different.

  Tong Zhaohui introduced that most of these patients are suffering from severe hypoxia and their condition is progressing rapidly.

  "I have also experienced SARS, which mainly involves the organs in the lungs. If we can take some measures, whether non-invasive or invasive, to reverse the lungs during SARS, the disease will basically be fine. " Tong Zhaohui said that now they found that novel coronavirus not only attacked the lungs of patients, but also the heart and kidneys.

  The expert group found that patients with severe and critical illness had higher troponin. Tong Zhaohui said that if these patients eventually develop into respiratory failure, the heart, kidneys and other organs will have problems, leading to multiple organ failure.

  Jiang Rongmeng introduced that SARS in 2003 had a characteristic, basically (patients) had a fever above 38℃. Therefore, after 2003, fever clinics were set up in China to screen out the disease, so it could be screened out at a relatively early stage.

  "But this disease (COVID-19) is different. There are still many (patients) with low fever, 37 degrees, and some without fever, so it has certain concealment." Jiang Rongmeng said.

  "After infection, the progress of this disease is relatively slow." Jiang Rongmeng said that compared with the familiar diseases, severe pneumonia can be found in three or four days after the onset of influenza or bird flu. In COVID-19, some patients are not too serious in the first five or six days, and patients may not come to see a doctor. However, patients are still contagious and will spread through family, community or friends’ dinners.

  "Another feature is that the early stage is not typical." Jiang Rongmeng said that the elderly with this disease are much more infected, and the disease is more serious. Now many patients are found to go to the general department for medical treatment because of other diseases (early). "For example, go to the respiratory department, or go to neurosurgery, or go to other departments. He may have pneumonia when he sees a doctor, but pneumonia is not serious. This disease is not the main one. He may go to see some diseases in neurosurgery. Of course, it is contagious. "

  Critical care began to get on the right track.

  Tong Zhaohui introduced that through this period of time, under the leadership of National Health Commission, the current critical care work has gradually begun to get on the right track.

  First of all, Wuhan Jinyintan Hospital, Zhongnan Hospital of Wuhan University, and Wuhan pulmonary hospital are regarded as three key hospitals that specially treat severe and critically ill patients. With the shortage of beds, it continues to expand. Wuhan union hospital West Hospital, Tongji Sino-French (tongji hospital Sino-French New Town Campus affiliated to Tongji Medical College of Huazhong University of Science and Technology) and East Hospital of Hubei Provincial People’s Hospital are also included. At present, there are six relatively large hospitals as hospitals for treating severe and critical diseases. With the arrival of medical teams from all over the country, some key and important medical teams have been placed in these six hospitals.

  Secondly, from the strategy, through the early exploration, it is concluded that we should move the threshold of rescue and treatment forward and actively treat critically ill patients. And there are national experts and provincial experts who go to various hospitals to patrol and consult and guide the work. These patients are all suffering from multiple organ failure, and there are also multidisciplinary experts for consultation. In addition, it is necessary to analyze and discuss the death cases in time and sum up some experiences.

  Third, pay close attention to and monitor the changes of patients’ condition. Some mild and ordinary patients will suddenly get worse and become severe. During this period, it is necessary for doctors to closely monitor patients’ indicators. This close observation can prevent the development of serious illness.

  Tong Zhaohui introduced that medical staff also took some intervention measures, such as trying to give patients a good environment to rest, and then antiviral treatment, as well as the treatment of combining Chinese and Western medicine, so that these light and ordinary patients can develop into severe diseases as little as possible.

  "Sometimes it is inevitable that some patients will develop into critical illness, and the transfer and referral mechanism has also been established and there are processes." Tong Zhaohui said that according to these measures, hospitals, especially several hospitals that focus on treating critically ill patients, have been running smoothly and orderly during this period. At present, some critically ill and critically ill patients are discharged from these hospitals every day.

Biden sat back in the Queen’s funeral seat, and Trump ridiculed: If I were the president, I wouldn’t be arranged to sit there.

  [Global Network Reporter Zhang Xiaoya] "US President Joe Biden and his wife Jill are obviously late. They are not allowed to ruin the elaborate funeral of the late queen." The British "Guardian" reported on the 19th that the Bidens who attended the Queen’s funeral were forced to wait for their seats after being late.

Guardian: Joe Biden was late for the Queen's funeral and was forced to wait to be seated.

Guardian: Joe Biden was late for the Queen’s funeral and was forced to wait to be seated.

  According to the report, Biden was allowed by the British side to go to Westminster Abbey, where the Queen’s funeral was held, on the 19th in the US President’s special heavy armored limousine "Beast", instead of taking a bus with other national leaders and heads of government.

  The Guardian said that when the Bidens arrived at Westminster Abbey, they were not immediately guided to their seats, but were euphemistically told that they needed to stand and wait, because in front of them, they held military medals — — The winners of the Victoria Cross and George Cross are entering the venue. The Bidens chatted awkwardly at the main entrance for a while, and finally entered the venue behind the winners of the Victoria Cross.

  According to the report, the Biden couple arrived at the funeral scene of the Queen of England at about 10: 05 am that day — — Westminster Abbey. According to the schedule announced by Buckingham Palace, invited foreign dignitaries should be seated between 9: 35 and 9: 55 am.

  "Perhaps because the Bidens did not take the bus from the assembly point of Chelsea Royal Hospital and carried other leaders, the Bidens were also arranged to sit in the 14th row behind the South Ear Hall of the church." The report also said that Biden sat behind Polish President Duda and in front of Czech Prime Minister Fiala.

Outside Westminster Abbey, Biden is sitting in a car. Figure from British media

Outside Westminster Abbey, Biden is sitting in a car. Figure from British media

  After the news that Biden was sitting in the 14th row was exposed, former US President Trump quickly posted a message on his personal website mocking Biden. "In just two years, this happened in the United States, with no respect at all." "If I were the president, they wouldn’t let me sit there."

  Earlier, according to the European version of the US "political" news network reported on the 14th, the news that Britain allowed Biden to attend the funeral of Queen Elizabeth II by car broke out, which triggered a chain reaction — — Some countries are strongly dissatisfied with this arrangement by the British side, demanding that their leaders get the same treatment as Biden and get "special permission" to go to the funeral site by car instead of by bus. Some of them think that it is "beneath dignity" for their leaders to take the bus with the leaders of "smaller countries".

21 Private Investment and Financing Weekly (September 6-September 13)

21st century business herald reporter Zhao Na intern Xiao Qian comprehensive report

Consumer service

A new generation of children’s snack brand Duomaomao completed tens of millions of A round financing.

On September 8 th, the new generation of children’s snack brand Duomaomao has completed tens of millions of A-round financing, which was jointly led by Houwei Capital (Mango Diyuan) and old shareholder Yiling Capital. This round of financing will be used for product research and development and channel laying.

Duomaomao was founded in September, 2020, and started with children’s jelly in the early days. At present, it has formed a product matrix of main and supplementary foods, snacks and condiments.

Bosie, a cutting-edge designer brand in China, completed a new round of financing of several hundred million yuan.

On September 7th, bosie, a cutting-edge designer brand, announced today that it has completed a new round of financing of several hundred million yuan. The investors are bilibili and Wuyuan Capital, and the old shareholder Jinshajiang Venture Capital is the sole financial advisor. This round of financing will be used for product development and supply chain upgrade.

Bosie is a non-sexist clothing brand, which is committed to bringing simple and generous classic items to young people who are exploring themselves and pursuing independence.

Medical health

Ruhan Gene completed tens of millions of angel rounds of financing.

On September 6th, Shenzhen Ruhan Gene Technology Co., Ltd. (hereinafter referred to as "Ruhan Gene") completed tens of millions of RMB angel round financing led by Lihe Kechuang Venture Capital, and the financing proceeds will be used for technology research and development, equipment procurement and team building.

Ruhan gene integrates the latest technologies such as bioengineering and genomics, semiconductor technology, AI big data analysis technology, micro-nano technology, etc., and develops the fourth-generation gene sequencing, nanopore virus detection and other biomacromolecule detection related equipment with independent intellectual property rights.

Zhenluo completed the B+ round financing of 100 million yuan scientifically

On September 6th, it was reported that Shenzhen Zhenluo Science Co., Ltd., the world’s leading innovative medical technology and service company in the field of central nervous system diseases, has recently completed a B+ round of financing of RMB 100 million. This round of financing was jointly led by Qiming Venture Capital and Stowe Capital, and F-Prime Capital followed suit. It is reported that the funds from this round of financing will be used for technical research, product development, international scientific research cooperation and global business development.

Zhenluo Science takes Parkinson’s disease as the market entry point of central nervous system diseases, and is committed to building a full-time diagnosis and treatment system based on advanced technology, providing innovative value for patients, clinical experts and medical equipment partners in this field.

Stance was led by CDH VGC in Series C with over $40 million.

On September 6th, Shanghai Stensai Biotechnology Co., Ltd. (hereinafter referred to as "Stensai") announced the completion of the Series C financing of over US$ 40 million. This round of financing was led by CDH VGC (CDH Innovation and Growth Fund), and many other investment institutions followed suit. This round of financing will be used for the research and development of innovative CoupleCAR platform technology, promote the development of cell therapy products for colorectal cancer and other solid tumors, and accelerate the clinical trial process in the United States and China.

Stance is a global cell therapy company, which is mainly engaged in the research and application of cutting-edge CAR-T technology and gene editing technology.

Weituo Bio, an assisted reproductive head enterprise, completed the C round of financing of 100 million yuan.

On September 7, Shenzhen Weituo Biotechnology Co., Ltd. (hereinafter referred to as Weituo Biotechnology) announced the completion of the C round of financing of 100 million yuan. It is reported that this round of financing was led by Zhongjin Qichen Fund, a subsidiary of CICC Capital, and Zhang Kehe Run and Xiang Financing followed suit. The favor of many professional investors reflects the high trust in the professional ability and strategic layout of Weituo Biological Team. This round of investment will be mainly used to strengthen product research and development, enrich product pipelines, expand professional teams and accelerate commercial landing, and further expand Weituo Bio’s leading edge in core technologies and markets.

Weituo Bio is committed to providing cutting-edge technology in the field of assisted reproduction and providing integrated solutions for assisted reproduction laboratories around the world.

RootPath completed nearly $50 million in Series B financing.

On September 7th, RootPath, a synthetic biology and gene cell therapy company, announced that it had recently completed a series B financing of nearly $50 million. This round of financing will be used for the development and commercialization of genetic synthesis products with arbitrary sequence Qualcomm quantity, long fragment and high accuracy, and for pushing its individualized TCR-T treatment project based on the technology of TCR gene synthesis and function verification with ultra-Qualcomm quantity to the clinical development stage, including the construction of GMP workshop suitable for IIT and Phase I clinical trials in China.

RootPath is a company that develops synthetic biology and cell therapy technology with the world’s leading gene synthesis platform.

"Good mood" completed the C round of 200 million yuan financing

On September 7th, "Good Mood" announced the completion of the 200-million-yuan Series C strategic financing. This round of financing was led by ByteDance, followed by Fosun Health, Decheng Capital and Xingfu Capital, and the old shareholders Tonghe Yucheng and KIP China were oversubscribed. This round of financing funds will be mainly invested in business expansion, intelligent supply chain construction, offline chain psychological clinics laying and data-based artificial intelligence product research and development, further consolidating the super-head position of mental health service industry and leading the development of the industry.

Good Mood is an Internet medical platform focusing on mental health services in CNS (Central Nervous System), which provides professional, advanced, efficient and convenient digital diagnosis and treatment services for patients with mental illness.

Mai Ruisheng completed tens of millions of yuan Series A financing.

On September 8, news, Jingmai Ruisheng Pharmaceutical Technology Co., Ltd. (hereinafter referred to as: Mai Ruisheng) announced the completion of tens of millions of A-round financing. The investor is Boqu Fund, where Fun Road Assets is the fund manager, and WinX Capital is the exclusive financial advisor. After the completion of this financing, Mindray will further build a CRO platform of "equipment+special medical food+medical beauty and health" by relying on its strong CRO capabilities.

With more than ten years’ experience in equipment CRO, Mindray Group is the largest CRO platform of "equipment+special medical food+medical beauty and health" in China, and it is also one of the equipment CRO companies with the highest net profit rate in China.

Shize Bio, an innovative cell therapy company, completed nearly 100 million yuan of Pre-A financing.

On September 8th, it was reported that Shize Biomedical Co., Ltd., a new generation of innovative stem cell therapy enterprise, recently officially announced the completion of nearly 100 million yuan Pre-A round of financing. This round of financing was jointly led by Qiming Venture Capital and Lilly Asia Ventures, followed by Daoyuan Capital and Jiacheng Capital, and all shareholders of Shize Biological Angel Wheel, Fengrui Capital, Yuansheng Venture Capital and TEDA Science Investment, followed suit. This round of financing is mainly used for the research and development of Shize Bio-core product pipeline and the construction of production workshop.

Shize Bio is committed to providing large-scale and low-cost stem cell therapy for major diseases such as Parkinson’s disease.

Several creatures completed nearly 100 million yuan in round B financing.

On September 8 th, Zhejiang Digital Biotechnology Co., Ltd. (hereinafter referred to as Digital Biotechnology) announced the completion of the B round of financing of nearly 100 million yuan. This round of financing was led by Guolian Investment, followed by Shuncheng Capital, Anyuan Fund and Chuangchuang Fund. After the completion of this round of financing, Digitalis will make great progress in the protection of external funds and the improvement of its own operational ability, which will provide sufficient guarantee for its persistent focus on tumor screening and the development, production and marketing of innovative products in the fields of maternal and child and reproductive health.

Neighbouring doctors completed tens of millions of yuan in Series A financing.

On September 9 th, neighboring medical fast medicine announced the completion of tens of millions of A round financing. This round of financing is invested by Jixianglei (Yantai) Medical Technology Co., Ltd., a wholly-owned subsidiary of Ruikang Medicine (002589.SZ) digital medical sector, and the funds will be used for market expansion, software development and upgrade, and team building.

Neighbourhood Medicine Express is a new retail empowerment solution provider of a pharmacy, which is committed to changing the traditional management mode of China pharmaceutical industry and helping it realize digital transformation with technical force.

Ruizheng Gene completed tens of millions of dollars in seed round financing.

On September 9, Ruizheng Gene (Suzhou) Co., Ltd. (abbreviated as Ruizheng Gene) announced that it has completed tens of millions of dollars in seed round financing. This round of financing was led by Junlian Capital, a well-known medical investment institution, and Cormorant followed the investment, which will be used to support the company’s R&D platform construction and the rapid advancement of pipelines.

Ruizheng Gene focuses on intracellular targets, including nuclear targets, and is committed to providing innovative drugs and treatment programs that can treat serious and even life-threatening congenital genetic diseases and acquired diseases for patients around the world.

Ge Rui surgical robot completed tens of millions of angel round financing.

On September 10th, Great Robotics, a precision imaging surgery robot, announced that it had completed tens of millions of angel round financing. This round of financing is exclusively led by Innolux Angel Fund, and the financing proceeds will be used for the core technology expansion and development of the company’s surgical robot platform, and then transformed into multiple product solutions.

Gerui Technology is an innovative medical robot company, which mainly develops a series of surgical robots according to the clinical needs and pain points based on the core technology platform of "precise image guidance" surgical robots.

Proton technology completed tens of millions of yuan series A financing.

On September 10th, Hangzhou Proton Technology Co., Ltd. completed the tens of millions of RMB Series A financing jointly led by Sigang Capital and Qirong Venture Capital, and the original shareholder Qikai Investment. This round of financing will be mainly used for product R&D investment, marketing and company operation, helping the company to continue to deepen the research and development of medical-grade vital signs monitoring technology and promote the development of artificial intelligence mobile medical industry.

Hangzhou Proton Technology Co., Ltd. is an innovative digital medical enterprise focusing on the research and development of wearable medical-grade vital signs monitoring technology. Its main business is to provide users with accurate, safe and convenient screening, diagnosis and health management services.

Biguan Bio completed tens of millions of A rounds of financing.

On September 10th, Day6 Biotech, a startup company developing a new generation of "microfluidic integrated machine" technology, announced the completion of tens of millions of RMB Series A financing, which was led by Songze Capital, followed by the old shareholders and Qingjie Capital, with Qingjie Capital as the exclusive financial advisor. The funds raised in this round will be used for clinical testing and NMPA registration of molecular POCT products with "on-demand inspection, low-cost consumables and one-step operation" developed by Biguan, and to expand the company’s R&D pipeline.

Mandi Medical, the first magnetocardiographic equipment factory in China, completed the A round financing of over 100 million yuan.

On September 10th, Mandi Medical announced the completion of the A round of financing exceeding 100 million yuan, which was jointly invested by National Science Development under the Chinese Academy of Sciences, Chinese Academy of Sciences Capital, Shanghai Microsystems Institute of Chinese Academy of Sciences, Shanghai Xinwei Group and Shanghai Guo Xin.

Mandi Medical Instrument (Shanghai) Co., Ltd. has mastered the domestic magnetocardiographic testing technology with independent intellectual property rights, and its equipment performance has reached the international level. In 2019, it became the first magnetocardiographic manufacturer in China to be approved with NMPA registration certificate.

Point technology won tens of millions of yuan in Series A financing.

On September 10th, it was reported that Diannei Technology, a medical artificial intelligence enterprise, had completed tens of millions of yuan of Series A financing, which was jointly completed by Trunk Road Fund and Empower Investment.

Founded in April 2016, Diannei Technology is one of the first enterprises to step into medical artificial intelligence image-aided diagnosis, focusing on the creation of AI lung cancer whole course solution.

LAM-Helio, a cancer early screening enterprise, completed hundreds of millions of yuan in financing.

On September 11th, LAM-Helio Group, which is committed to becoming a global leader in cancer early screening, has announced that it has completed financing of several hundred million yuan, with accumulated financing exceeding 1 billion yuan. Shareholders include Chinese Academy of Sciences Venture Capital, Chinese Academy of Sciences Parent Fund, Fulgent Genetics and other institutions and companies. The funds will be used to build the commercialization team and organization of liver cancer products, promote the Sino-US clinical approval of early screening products for intestinal cancer and lung cancer, and accelerate the optimization of early screening technologies for lung cancer and intestinal cancer with the National Cancer Center.

LAM-Helio is a life science enterprise group driven by "AI+ genomics", which focuses on early screening and early diagnosis of cancer.

smart manufacturing

Xiaomi Eco-chain Enterprise Shunzao Technology completed the $50 million Series B financing.

On September 8th, it was reported that Shunzao Technology, a technology enterprise focusing on the field of clean household appliances in Xiaomi’s ecological chain, recently completed a $50 million Series B financing. This round of investment was led by Baobi Industrial Chain Fund, followed by blue lagoon Capital, additional investment by Xiaomi Group and Shunwei Capital, and Yunmu Capital served as the exclusive financial advisor of the company. This round of financing will be mainly used for research and development of new technologies, iterative innovation of core products, global channel construction and the construction of fully automated factories for black technology.

Shunzao Technology was established in 2019. At present, it has built three categories of clean household appliances: handheld wireless vacuum cleaner, intelligent sweeping robot and intelligent washing machine.

Gartland completed hundreds of millions of RMB Series C financing.

On September 8th, it was reported that Gartland Microelectronics Technology (Shanghai) Co., Ltd. (hereinafter referred to as "Gartland"), a manufacturer of millimeter-wave radar chips with CMOS technology, had completed the C-round financing of several hundred million RMB. This round of financing was led by SDIC, with the participation of Langmafeng Venture Capital and Bank of Communications International, and the Huaxing New Economic Fund under Huaxing Capital continued to increase, with Huaxing Capital as the exclusive financial advisor.

Gartland was established in 2014, focusing on the research and development of millimeter-wave radar chips in CMOS technology, and it is the world’s leading provider of millimeter-wave radar chips.

Vibe, an intelligent hardware brand, has received a series of financing of tens of millions of dollars.

On September 7th, it was reported that Vibe (Sunlight Technology), an intelligent hardware brand, had recently completed the series A and A+ financing of tens of millions of dollars. The investors were Huachuang Capital and Sequoia China Seed Fund, and Light Source Capital served as the exclusive financial advisor for this round of financing. Previously, Vibe had received millions of dollars in financing from Challenger Capital, Xinyuan Capital and Jiuhe Venture Capital. This round of financing will be used for product research and development, supply chain integration and talent attraction.

Vibe combines the advantages of China’s supply chain with the potential enterprise market, and focuses on building a DTC(Direct To Customer) brand in the field of To B combining software and hardware.

Guona Semiconductor completed tens of millions of A+ rounds of financing.

On September 10th, it was reported that Guona Semiconductor, a developer of semiconductor components, recently announced the completion of tens of millions of A+ rounds of financing. The investors included Zhongxin Capital, Shenzhen Tianxia Future and Huada Microelectronics, the largest shareholder of Tongfu Microelectronics.

Guona Semiconductor was established in 2020, focusing on the field of integrated circuit transmission, and its main business is semiconductor transmission equipment modules and parts.

TMT

Craftsman Technology completed the B2 round of financing of nearly RMB 100 million.

On September 9th, it was reported that Craftsman Technology, a digital commercial real estate service provider, recently completed a B2 round of financing of nearly RMB 100 million. This round was led by Zhixin Capital, and Yibai Capital served as the exclusive financial advisor. The funds will be mainly used for research and development and business expansion.

Founded in 2015, Craftsman Technology has been focusing on the real estate technology track.

Youbi Technology completed tens of millions of A round financing.

On September 9, Ubisoft, a smart IOT solution provider in the energy industry, announced that it had recently completed tens of millions of RMB Series A financing, which was exclusively invested by Jingwei Venture Capital. This round of financing will be mainly used for the company’s continuous expansion of new product lines such as online monitoring of smart grid, intelligent operation and maintenance of new energy and energy storage monitoring, and continue to dig deep into domestic and foreign markets, and further improve the team structure.

Youbi Technology focuses on empowering cutting-edge technologies such as AIoT, deep learning and neural networks to industries such as power, energy and rail transit, and providing end-to-end "AI+" products, services and overall solutions to customers around the world.

Intelligent marketing platform Stepone Jizhi Technology completed 100 million yuan Series B financing.

On September 9 th, Stepone Jizhi Technology (hereinafter referred to as "Jizhi Technology"), a one-stop intelligent marketing customer acquisition platform, announced the completion of 100 million yuan Series B financing. This round of financing was led by SIG Heiner Asia Venture Capital, and Taiyue Wutong Capital, a fund of listed company Shenzhou Taiyue, followed suit. At the same time, all the old shareholders such as Guangsu China, Xinyi Capital and Xiang Hailong continued to follow suit.

Steepone Jizhi Technology is a leading intelligent customer service provider in China, providing full-process intelligent marketing services for To B enterprises based on Al big data technology.

E-PORTS was led by Jinshajiang United Capital in the B1 round of financing.

On September 6th, E-PORTS, the Internet platform of shipping industry, announced the completion of tens of millions of B1 round financing. This round of financing was led by Jinshajiang United Capital, with Index Capital as the exclusive financial advisor. The financing funds will be mainly used for system research and development, team building and market expansion.

E-PORTS takes "one-click access to world-class shipping services" as its mission, and is committed to providing online and offline world-class shipping services for global ships and port service solutions for global merchant ships.

(Author: Zhao Na Editor: Lin Kun)

Director Teng Huatao talks about the controversy of "Shanghai Fortress": I used the wrong Luhan

Directed by Teng Huatao, the domestic sci-fi film starring Lu Han and Shu Qi received a lot of publicity before the release, but encountered the dilemma of word-of-mouth Waterloo after the release. Creator Teng Huatao and the original author Jiangnan came forward one after another and apologized to the audience on Weibo. Teng Huatao also gave another interview to "Poisonous Tongue Movie" a few days ago, responding to the controversy of negative word-of-mouth and the choice of actors. He explained: "I apologize without anyone coercion, nor any commercial purpose, just personal choice." During the conversation, Teng Huatao also talked about one of the film’s huge controversies, Lu Han, saying that he had no opinion on Lu Han technically, but ignored the difference in the type of actors. "I used the wrong Lu Han, in a type that is not suitable for him."

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Teng Huatao explained why he "misused" Lu Han, saying that he wanted to make a sci-fi war movie, but ignored Lu Han’s actor type when choosing actors. "I used Lu Han wrong, in a genre that is not suitable for him." It also means that Teng Huatao directly admitted that Lu Han is not suitable for playing sci-fi war themes. In addition, when talking about Jiang Yang (Lu Han’s character) bangs hairstyle, Teng Huatao also frankly: "I think it may be a [problem], but this is an irreversible thing. After the filming is settled, do I have any other possibilities to adjust?"

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When asked if he would change actors if there was a possibility of a comeback, Teng Huatao said his intuition was "not that Lu Han is bad, but that we have never made this type of film", and without experience, "can we make Lu Han?"When such an idol went to play, I didn’t judge it well at that time. "


In addition, Teng Huatao also once again refuted the rumor that Lu Han’s sky-high salary, emphasizing that he "received very little money". He said that when he decided to use Lu Han in 2017, he did not take into account some of the opinions that people would have on traffic stars. "Traffic stars are always a double-edged sword." He also denied that he used Lu Han for traffic reasons – the movie tickets that fans can buy are limited in conversion energy.

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In the interview, Mr. Teng also noted that the actors were chosen by themselves and were "innocent" and that "it’s not realistic to expect people to say anything [to apologize] when the film doesn’t perform well."


Buick Envision Plus VIP Intelligent Electronic Architecture Experience

The ever-changing intelligent network technology is transforming cars from daily transportation tools to mobile intelligent end points and digital spaces. GM’s new generation of VIP intelligent electronic architecture is like the "brain" and "nervous system" of smart cars. It is the core of vehicles to realize intelligent driving technology, equipped with advanced intelligent network technology and supports OTA updates, providing strong support for "software-defined" cars and automotive intelligence. Thanks to the powerful computing and information processing capabilities of GM’s new generation of VIP intelligent electronic architecture, Buick Envision Plus is equipped with advanced intelligent safety technology and iterative updates of eConnect intelligent interconnection technology, bringing consumers a faster, more powerful and safer new smart travel experience.

GM’s new generation of VIP intelligent electronic architecture was developed by GM’s global team. It is worth mentioning that GM’s China Foresight Technology Center and Pan-Asia Experiment Center in China also participated in the development and testing of this architecture to ensure that the architecture can meet the needs of Chinese consumers. The Buick Envision Plus, as a key model under GM, is also equipped with a new generation of VIP intelligent electronic architecture for the first time. According to the official, this system will be carried to more GM models in the future.

The new generation of VIP intelligent electronic architecture also brings the following different experiences to Envision Plus:

In the new era of "software-defined cars", Buick Envision Plus will rely on a new generation of VIP intelligent electronic architecture with rapid evolution and iterative update capabilities, as well as the accumulation and innovation of SAIC-GM Buick brand in "second engine" vehicle to everything technology and intelligent driving technology, to continuously meet consumers’ good expectations for smart travel.

Dark Blue G318 officially listed: hardcore SUV camping must drive, priced from 175,900 yuan

  News (Gao Jingyu/Wen) On June 13, the dark blue G318 was officially launched, with a total of six models, and the price range was locked between 175,900 yuan and 318,000 yuan. Its two-wheel drive air suspension version is equipped with air suspension + CDC + double fork arms, and the price is less than 200,000 yuan. According to official data, the order channel was opened for only 60 minutes, and the order has exceeded 3,000 units.

  According to the official introduction, the dark blue G318 is equipped with super range extension 2.0 technology, which can generate 3.63 kWh of electricity per liter of oil. This efficient conversion efficiency provides users with excellent pure electric battery life and comprehensive battery life. The dark blue G318 has a pure electric battery life of 190km and a comprehensive battery life of more than 1000km. One charge can meet the needs of multi-day commuting in urban areas.

  As a hard-edged SUV, the Deep Blue G318 adopts the configuration of front double fork arms and rear five-bar independent suspension, combined with the empty magic carpet CDC suspension, and uses the tuning strategy of "suspension low hysteresis force integration technology" and "low bias frequency and high damping". The internal friction of the suspension is reduced by 54% on the original basis, which realizes the keen capture and fast feedback of the vehicle’s dynamic response, which greatly improves the vehicle’s handling and comfort. In addition, the four-wheel drive version is also equipped with a dual-motor full-condition true four-wheel drive system, a central stepless differential lock, and a magnetic mechanical differential lock. These configurations further enhance the vehicle’s passability and off-road capabilities.

  In terms of comfort configuration, the Dark Blue G318 also performs well. Features such as R-EPS steering system, front seat ventilation and heating, and 540 ° panoramic images provide users with a convenient and comfortable driving experience. At the same time, the Deepal OS ecosystem, double-layer soundproof glass and ENC active noise reduction technology also create a quiet riding environment for passengers in the car.

  In terms of space, the dark blue G318 has greatly released space through innovative design. The length is 5010mm, the wheelbase is 2880mm, the cockpit space is 3010mm, the first row of legroom is 1194mm, and the second row of legroom is 905mm. In addition, the vehicle is also equipped with a luggage rack PLUS and a 1.6T tow hook to support various outdoor equipment.

Follow Flush Finance (ths518) for more opportunities

Yancheng Extreme Krypton 001 has greatly reduced its price, with a maximum discount of 37,000! Today’s juhui

Recently, car home Yancheng Preferential Promotion Channel has brought an exciting preferential activity to riders! As a new energy vehicle that has attracted much attention, it is now in progress, allowing you to enjoy a discount of up to 37,000 yuan when purchasing. The starting price has been as low as 269 thousand yuan, which is undoubtedly an irresistible temptation. If you want to know more preferential information, click the "Check Car Price" button in the quotation form to get a higher discount!

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Extreme Krypton 001 is a fashionable and avant-garde model with unique design, dynamic front design and closed air intake grille, which shows the characteristics of its electric vehicle. The lines of the whole vehicle are smooth and strong, and the overall style is very sporty. Extreme Krypton 001 adopts a streamlined body design, with a sharp sense of lines at the front and exquisite design at the rear. The whole body is full of power and impressive. The body is made of high-strength materials, which improves the stability and safety of the vehicle. The details of the car body are also handled with great care, and the door handle adopts a hidden design, which highlights its high-end quality. Generally speaking, the design of Krypton 001 is full of futuristic and technological sense, and it is a very attractive model.

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Extreme Krypton 001 is a medium and large SUV with a size of 4977*1999*1533mm, with a wheelbase of 3005mm, a front track of 1703mm and a rear track of 1716mm, which provides drivers with spacious driving space and good handling performance. The tyre size of this car is 255/55 R19, the front and rear wheels are of the same specifications, and it is matched with the atmospheric rim design, which makes the whole car look more fashionable and dynamic. The body lines are smooth, and the side lines are simple and atmospheric, showing the sense of fashion and technology of Krypton 001.

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The interior design of Krypton 001 is very luxurious, and it is made of high quality leather, which makes people feel very comfortable. The 15.05-inch central control screen is very large and easy to use, and it supports voice recognition control systems, including multimedia, navigation, telephone and air conditioning. The steering wheel is made of leather, and it is electrically adjustable up and down+back and forth, which is very comfortable. There are Type-C interfaces in the front row and the back row, which is convenient for charging. The seats are also very comfortable. Both the main and co-pilot seats support electric adjustment, including front and rear, backrest, height, leg rest and lumbar support. The front seats also support heating, ventilation and massage functions, which is very user-friendly. The second row of seats can also be adjusted by backrest, and the rear seats support proportional reclining, which is very practical. Generally speaking, the interior design of Krypton 001 is excellent, which makes people feel very comfortable and luxurious.

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Extreme Krypton 001 is a powerful vehicle, and its engine has a maximum power of 580kW and a maximum torque of 810N·m, which makes it perform well during acceleration and driving. Such dynamic parameters can not only meet the daily driving needs, but also provide a more exciting driving experience. At the same time, the engine of Krypton 001 also adopts advanced technology, which makes its fuel economy higher and saves fuel expenses for users. Whether driving in the city or traveling long distances, the Krypton 001 can provide excellent performance and is a satisfactory model.

In the eyes of car home car owners, Krypton 001 is a very domineering, atmospheric and cool model. The headlights on the front face and the sharp lines on the hood make the whole car look very sharp, and the side design effect is even more cool and highly recognizable. In addition, the extremely Krypton 001 coupe body is low and handsome with wheels. This model is undoubtedly a very successful coupe model, which shows a very high level in both appearance and performance. Thank you very much for sharing with car home car owner @ Zhenjiang Cheyou 7067554, which made us know more about the charm of Krypton 001.